Description

6,7-Dihydroxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrobromide is a high-purity, pharmaceutically relevant salt form of a tetrahydroisoquinoline derivative. This compound is a critical intermediate or reference standard in advanced organic synthesis and pharmaceutical research, valued for its defined chemical structure and purity. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of bioactive molecules, particularly within the fields of neuroscience and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex alkaloids and potential drug candidates targeting neurological pathways.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing (HPLC, LC-MS).
• Biochemical Research: Serves as a precursor or tool compound in neuroscience research to study receptor interactions and enzyme inhibition.
• Organic Synthesis: Employed in academic and industrial research for constructing tetrahydroisoquinoline-based molecular libraries.
• Active Pharmaceutical Ingredient (API) Development: Investigated as a potential starting material or intermediate in the development of new therapeutic agents.

Basic Information

Product Name	6,7-Dihydroxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrobromide
CAS No.	38221-21-5
Molecular Formula	C10H13NO2 • HBr
Molecular Weight	260.13 g/mol
Synonyms	1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrobromide; 6,7-Dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline HBr; 1-Methyl-1,2,3,4-tetrahydro-6,7-isoquinolinediol hydrobromide; Norlaudanosoline 1-methyl ether hydrobromide; 6,7-Dihydroxy-1-methyl-THIQ HBr; 1-Methylnorlaudanosoline hydrobromide; THIQ derivative HBr salt
EINECS	Contact for details

Quality Control

Our 6,7-Dihydroxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.