Description

(E)-1-Iodo-2-Butene is a high-purity, unsaturated organoiodine compound characterized by its specific stereochemistry. This versatile building block is essential for introducing the vinyl iodide functional group into complex molecules via cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel compounds and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Stille, Suzuki, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific olefinic structures.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialized polymers and organic electronic materials.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic molecules, including natural product analogs.
• Ligand and Catalyst Preparation: Useful for modifying phosphine and other ligands to create novel catalytic systems for asymmetric synthesis.
• Chemical Biology Probes: Acts as a reagent for labeling biomolecules or synthesizing probe molecules for biochemical studies.

Basic Information

Product Name	(E)-1-Iodo-2-Butene
CAS No.	38169-04-9
Molecular Formula	C4H7I
Molecular Weight	182.00 g/mol
Synonyms	(E)-1-Iodo-2-butene; trans-1-Iodo-2-butene; 1-Iodo-trans-2-butene; (E)-2-Buten-1-yl iodide; trans-2-Buten-1-yl iodide; (E)-1-Iodobut-2-ene; 38169-04-9
EINECS	Contact for details

Quality Control

Our (E)-1-Iodo-2-Butene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by GC/HPLC), isomer content, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
(E)-Isomer Content	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.