Description

(3S,8Ar,10S)-3-[[(E)-1,3-Dihydro-3-Oxo-2H-Indol-2-Ylidene]Methyl]-1,2,3,7,8,8A-Hexahydro-10-(1-Methylethyl)-6H-3,8A-Ethanopyrrolo[1,2-A]Pyrazine-1,4-Dione is a complex heterocyclic organic compound with a fused ring system, serving as a critical advanced pharmaceutical intermediate for the synthesis of novel therapeutic agents. Its intricate molecular architecture makes it a valuable scaffold for medicinal chemistry research, particularly in developing compounds with targeted biological activity. This high-purity intermediate is essential for R&D and production within the pharmaceutical and biotechnology sectors, where precise chemical structure is paramount for drug efficacy and safety.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Biochemical Probe Development: Serves as a precursor for creating specialized probes to study biological pathways and enzyme interactions.
• Contract Research & Manufacturing (CRMO): Supplied to organizations engaged in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	(3S,8Ar,10S)-3-[[(E)-1,3-Dihydro-3-Oxo-2H-Indol-2-Ylidene]Methyl]-1,2,3,7,8,8A-Hexahydro-10-(1-Methylethyl)-6H-3,8A-Ethanopyrrolo[1,2-A]Pyrazine-1,4-Dione
CAS No.	38136-69-5
Molecular Formula	C24H25N3O3
Molecular Weight	403.48 g/mol
Synonyms	3-[(E)-1,3-Dihydro-3-oxo-2H-indol-2-ylidene]methyl]-1,2,3,7,8,8a-hexahydro-10-(1-methylethyl)-6H-3,8a-ethanopyrrolo[1,2-a]pyrazine-1,4-dione; (3S,8aR,10S)-3-[(E)-(3-Oxo-1,3-dihydro-2H-indol-2-ylidene)methyl]-1,2,3,7,8,8a-hexahydro-10-(propan-2-yl)-6H-3,8a-ethanopyrrolo[1,2-a]pyrazine-1,4-dione; 38136-69-5; Fused pyrrolopyrazine dione derivative; Isatin-based pyrrolopyrazine dione.
EINECS	Contact for details

Quality Control

Our (3S,8Ar,10S)-3-[[(E)-1,3-Dihydro-3-Oxo-2H-Indol-2-Ylidene]Methyl]-1,2,3,7,8,8A-Hexahydro-10-(1-Methylethyl)-6H-3,8A-Ethanopyrrolo[1,2-A]Pyrazine-1,4-Dione is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.