Description

Diethyl Phenylthiomethylphosphonate is a specialized organophosphorus compound with a thiomethylphosphonate ester structure. This chemical serves as a valuable synthetic intermediate, particularly in the construction of complex molecules for pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and life science industries for applications requiring the introduction of a functionalized phosphonate moiety.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new herbicides, insecticides, and plant growth regulators that leverage phosphorus chemistry.
• Ligand Synthesis: Precursor for creating specialized phosphonate-based ligands used in catalysis and metal complexation.
• Material Science: Intermediate in the production of flame retardants, plasticizers, or specialty polymers with modified surface properties.
• Chemical Biology: Tool compound for probing enzyme mechanisms or developing activity-based probes targeting phosphatases and related enzymes.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial manufacturing of high-value chemicals.

Basic Information

Product Name	Diethyl Phenylthiomethylphosphonate
CAS No.	38066-16-9
Molecular Formula	C12H19O3PS
Molecular Weight	274.31 g/mol
Synonyms	Diethyl (phenylthiomethyl)phosphonate; Phosphonic acid, (phenylthiomethyl)-, diethyl ester; (Phenylthiomethyl)phosphonic acid diethyl ester; Diethyl phenylmercaptomethylphosphonate; Phenylthiomethylphosphonic acid diethyl ester; Diethyl (phenylmercaptomethyl)phosphonate
EINECS	Contact for details

Quality Control

Our Diethyl Phenylthiomethylphosphonate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for manufacturing critical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.