Description

1-Propanethiol, 3-(Dimethylamino)-, Hydrochloride is a specialized organosulfur compound featuring a thiol group and a tertiary amine functionality, rendered stable and handleable as its hydrochloride salt. This unique structure makes it a valuable intermediate for synthesizing more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel compounds and developing new synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring thioether or sulfonium ion linkages.
• Ligand Precursor in Catalysis: Used to prepare specialized ligands for transition metal catalysts, enhancing selectivity in asymmetric synthesis.
• Agrochemical Synthesis: Serves as an intermediate in the production of certain herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Employed to introduce functional thiol groups into polymer chains for cross-linking or to impart specific chemical properties.
• Bioconjugation Chemistry: Useful in modifying proteins, peptides, or other biomolecules via thiol-reactive chemistry for research and diagnostic applications.
• Organic Synthesis Reagent: Acts as a nucleophile or a precursor to other sulfur-containing functional groups in multi-step synthetic sequences.

Basic Information

Product Name	1-Propanethiol, 3-(Dimethylamino)-, Hydrochloride
CAS No.	38048-81-6
Molecular Formula	C5H14ClNS
Molecular Weight	155.69 g/mol
Synonyms	3-(Dimethylamino)-1-propanethiol Hydrochloride; 3-(Dimethylamino)propane-1-thiol Hydrochloride; N,N-Dimethyl-3-mercaptopropylamine Hydrochloride; 3-Mercapto-N,N-dimethylpropylamine Hydrochloride; DMAPA-SH HCl; (3-Mercaptopropyl)dimethylamine Hydrochloride; 1-Propanethiol, 3-(dimethylamino)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-Propanethiol, 3-(Dimethylamino)-, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.