Description

2-Iodothiophenol is a versatile organosulfur and organoiodine compound primarily used as a key synthetic intermediate. Its unique structure, featuring both a thiol and an iodine substituent on an aromatic ring, makes it a valuable building block for constructing complex molecules in pharmaceutical and material science research. This compound is essential for chemists and manufacturers in the agrochemical, pharmaceutical, and specialty chemical industries who require a reliable precursor for cross-coupling reactions and heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfur heterocycles or aryl iodide motifs for further functionalization.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thiophenol core is integral to biological activity.
• Ligand and Catalyst Preparation: Acts as a starting material for the synthesis of specialized ligands used in transition metal catalysis, such as palladium-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, conductive polymers, and liquid crystals due to its electron-rich and modifiable aromatic system.
• Chemical Synthesis Building Block: Utilized in various organic transformations, including nucleophilic aromatic substitution and as a substrate for constructing complex sulfur-containing scaffolds.

Basic Information

Product Name	2-Iodothiophenol
CAS No.	37972-89-7
Molecular Formula	C6H5IS
Molecular Weight	236.07 g/mol
Synonyms	2-Iodobenzenethiol; o-Iodothiophenol; 1-Iodo-2-mercaptobenzene; Benzenethiol, 2-iodo-; 2-Iodophenyl mercaptan; (2-Iodophenyl)thiol; 2-Mercaptoiodobenzene; o-Iodophenylthiol
EINECS	Contact for details

Quality Control

Our 2-Iodothiophenol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.