Description

3-(Bromomethyl)-1,2-Benzisoxazole is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the reactive bromomethyl group, which facilitates efficient functionalization and serves as a key intermediate for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those containing the benzisoxazole pharmacophore.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Material Science Precursor: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Nucleophilic Substitution: The bromomethyl group is readily displaced by various nucleophiles, enabling the introduction of diverse functional groups.
• Chemical Research & Development: Employed in academic and industrial R&D for methodological studies and library synthesis.

Basic Information

Product Name	3-(Bromomethyl)-1,2-Benzisoxazole
CAS No.	37924-85-9
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	1,2-Benzisoxazole, 3-(bromomethyl)-; 3-Bromomethyl-1,2-benzisoxazole; 3-(Bromomethyl)benzo[d]isoxazole; Benzisoxazole, 3-(bromomethyl)-; (1,2-Benzisoxazol-3-yl)methyl bromide
EINECS	Contact for details

Quality Control

Our 3-(Bromomethyl)-1,2-Benzisoxazole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.