Description

5-[(2-Chlorophenyl)Amino]-1,3,4-Thiadiazole-2-Thiol is a specialized heterocyclic organic compound featuring a thiadiazole core functionalized with a thiol group and a 2-chloroaniline substituent. This unique structure makes it a valuable pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing compounds with potential therapeutic or functional properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the thiadiazole-thiol moiety can act as a pharmacophore or metal-chelating group.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis Reagent: Serves as a precursor for creating more complex heterocyclic systems, ligands for catalysis, or functionalized polymers in material science.
• Bioconjugation & Probe Development: The reactive thiol group allows for conjugation with biomolecules or surfaces, useful in creating diagnostic probes or biochemical tools.
• Corrosion Inhibitor Studies: Investigated as a potential component in formulations designed to protect metals, as thiadiazole derivatives are known for their inhibitory properties.

Basic Information

Product Name	5-[(2-Chlorophenyl)Amino]-1,3,4-Thiadiazole-2-Thiol
CAS No.	37844-22-7
Molecular Formula	C8H6ClN3S2
Molecular Weight	243.74 g/mol
Synonyms	2-Chloro-N-(5-mercapto-1,3,4-thiadiazol-2-yl)aniline; 2-Amino-5-(2-chlorophenyl)-1,3,4-thiadiazole; 5-(2-Chloroanilino)-1,3,4-thiadiazole-2-thiol; 2-Chlorophenylamino-1,3,4-thiadiazole-2-thiol; 1,3,4-Thiadiazole-2-thiol, 5-[(2-chlorophenyl)amino]-; 2-Mercapto-5-((2-chlorophenyl)amino)-1,3,4-thiadiazole; N-(2-Chlorophenyl)-5-mercapto-1,3,4-thiadiazol-2-amine
EINECS	Contact for details

Quality Control

Our production of 5-[(2-Chlorophenyl)Amino]-1,3,4-Thiadiazole-2-Thiol adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against comprehensive specifications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, prolonged exposure to light, air, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.