Description

(Ethylmethylketoximino)Trimethylsilane is a specialized organosilicon compound featuring a ketoxime functional group protected by a trimethylsilyl moiety. This unique structure makes it a valuable blocking agent and synthetic intermediate in advanced organic synthesis, particularly for the protection of carbonyl groups. It is primarily needed by pharmaceutical, agrochemical, and specialty chemical manufacturers engaged in multi-step synthesis where selective protection and deprotection strategies are critical.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) requiring temporary protection of ketone or aldehyde functionalities.
• Agrochemical Synthesis: Serves as a key building block in the production of advanced pesticides and herbicides.
• Peptide Chemistry: Employed as a protecting group for amino acid side chains or during fragment condensation.
• Polymer Modification: Acts as a functional monomer or cross-linking agent in the synthesis of specialty silicones and silane-modified polymers.
• Organic Synthesis Reagent: Utilized in laboratory-scale and industrial-scale organic reactions, including Grignard and nucleophilic addition reactions, where oxime protection is required.
• Surface Treatment Agent: Can be applied in the formulation of adhesion promoters and surface modifiers for fillers and pigments.

Basic Information

Product Name	(Ethylmethylketoximino)Trimethylsilane
CAS No.	37843-14-4
Molecular Formula	C8H19NOSi
Molecular Weight	173.33 g/mol
Synonyms	Trimethylsilyl ethyl methyl ketoxime; O-Trimethylsilyl ethyl methyl ketoxime; Ethyl methyl ketone O-trimethylsilyl oxime; 2-Butanone, O-[(trimethylsilyl)]oxime; (Ethylmethylketoximino)trimethylsilane; TMS-EMKO; EMKO-TMS; O-TMS ethyl methyl ketoxime
EINECS	Contact for details

Quality Control

Our (Ethylmethylketoximino)Trimethylsilane is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.