Description

(S)-(-)-2-Phenyl-1-Propanol CAS NO 37778-99-7 is a high-purity chiral alcohol building block of significant importance in asymmetric synthesis. Its enantiomeric purity makes it a critical intermediate for the production of optically active pharmaceuticals and fine chemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce stereochemical control into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutics where the (S)-enantiomer confers desired biological activity.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereochemistry can enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations, such as asymmetric hydrogenations and alkylations.
• Fragrance and Flavor Industry: Employed in the synthesis of specific stereoisomers of aroma chemicals, where the scent profile is highly dependent on molecular chirality.
• Material Science Research: Acts as a monomer or building block for chiral polymers and liquid crystals with potential applications in advanced optics and electronics.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for studying stereoselective reaction mechanisms.

Basic Information

Product Name	(S)-(-)-2-Phenyl-1-Propanol
CAS No.	37778-99-7
Molecular Formula	C9H12O
Molecular Weight	136.19 g/mol
Synonyms	(S)-(-)-2-Phenylpropan-1-ol; (S)-1-Phenyl-2-propanol; (S)-2-Phenyl-1-propanol; L-2-Phenyl-1-propanol; (S)-α-Methylbenzyl alcohol; (S)-(-)-α-Methylbenzyl alcohol; (S)-1-Phenylethyl carbinol; (S)-Phenylmethylcarbinol
EINECS	Contact for details

Quality Control

Our (S)-(-)-2-Phenyl-1-Propanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC or GC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0%
Specific Rotation [α]D20	-40° to -45° (c=1 in ethanol)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.