Description

N,3-Bis(2-Chloroethyl)-n-(2-Methylsulfonyloxyethyl)-2-Oxo-1-Oxa-3-Aza- 2$L^{5}-Phosphacyclohexan-2-Amine CAS NO 37753-17-6 is a specialized organophosphorus compound featuring a unique heterocyclic structure. This chemical is of significant interest for its potential as a key synthetic intermediate in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis. Its complex structure offers a versatile scaffold for the development of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and neurological disorder research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its phosphorus-containing heterocycle for biological activity.
• Chemical Biology Probe: Acts as a specialized reagent for studying enzyme mechanisms and biological pathways due to its reactive functional groups.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and material science applications.
• Fine Chemical Synthesis: Utilized as a high-value intermediate for constructing complex molecular architectures in custom synthesis projects.

Basic Information

Item	Detail
Product Name	N,3-Bis(2-Chloroethyl)-n-(2-Methylsulfonyloxyethyl)-2-Oxo-1-Oxa-3-Aza- 2$L^{5}-Phosphacyclohexan-2-Amine
CAS No.	37753-17-6
Molecular Formula	C10H19Cl2N2O4PS
Molecular Weight	365.22 g/mol
Synonyms	1-Oxa-3-aza-2-phosphacyclohexan-2-amine, N,3-bis(2-chloroethyl)-N-[2-[(methylsulfonyl)oxy]ethyl]-2-oxo-; Cyclophosphamide Impurity; NSC 338947; Phosphoramide mustard analog; 2-Oxo-1-oxa-3-aza-2$l^{5}-phosphacyclohexan-2-amine, N,3-bis(2-chloroethyl)-N-[2-[(methylsulfonyl)oxy]ethyl]-; Ifosfamide related compound
EINECS	Contact for details

Quality Control

Every batch of N,3-Bis(2-Chloroethyl)-n-(2-Methylsulfonyloxyethyl)-2-Oxo-1-Oxa-3-Aza- 2$L^{5}-Phosphacyclohexan-2-Amine is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for each lot. We support compliance with cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.