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2-Propanesulfonic Acid, 2-((3-(2-Chloroethyl)Tetrahydro-2H-1,3,2-Oxaza Phosphorin-2-Yl)Amino)Ethyl Ester, p-Oxide CAS NO 37752-43-5


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CAS No.:37752-43-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Propanesulfonic Acid, 2-((3-(2-Chloroethyl)Tetrahydro-2H-1,3,2-Oxaza Phosphorin-2-Yl)Amino)Ethyl Ester, p-Oxide is a specialized organophosphorus compound with a sulfonic acid ester group, offering unique reactivity and functional properties. This chemical matters for its role as a key intermediate in the synthesis of advanced materials and biologically active molecules, where its specific structure enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty polymer sectors for developing new active ingredients and functional additives.

Application

  • Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
  • Agrochemical Synthesis: Used in the research and development of next-generation herbicides, insecticides, and plant growth regulators.
  • Polymer Modification: Acts as a functional monomer or cross-linking agent to impart flame retardancy, adhesion, or specific ionic characteristics to specialty polymers and coatings.
  • Ligand and Catalyst Development: Employed in organometallic chemistry to create novel phosphine-based ligands for catalytic processes.
  • Bioconjugation Chemistry: Utilized for modifying biomolecules (e.g., proteins, peptides) due to its reactive ester and amine functionalities.
  • Material Science Research: Investigated for creating advanced functional materials, including ionic liquids and conductive polymers.

Basic Information

Item Details
Product Name 2-Propanesulfonic Acid, 2-((3-(2-Chloroethyl)Tetrahydro-2H-1,3,2-Oxaza Phosphorin-2-Yl)Amino)Ethyl Ester, p-Oxide
CAS No. 37752-43-5
Molecular Formula C10H22ClN2O5PS
Molecular Weight 356.78 g/mol
Synonyms 2-[(3-(2-Chloroethyl)-1,3,2-oxazaphosphinan-2-yl)amino]ethyl 2-propanesulfonate 1-oxide; 2-((3-(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-yl)amino)ethyl 1,1-dimethylethanesulfonate 1-oxide; Phosphoramide acid, P-[2-[(2-chloroethyl)amino]ethyl]-N,N-dimethyl-, 2-oxide, 2-propanesulfonate (ester); A potential cyclophosphamide analogue intermediate; Contact for additional trade names.
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Quality Control

Our 2-Propanesulfonic Acid, 2-((3-(2-Chloroethyl)Tetrahydro-2H-1,3,2-Oxaza Phosphorin-2-Yl)Amino)Ethyl Ester, p-Oxide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters are available upon request to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents and strong bases.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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