Description

1-Propanesulfonic Acid, 2-((3-(2-Chloroethyl)Tetrahydro-2H-1,3,2-Oxaza Phosphorin-2-Yl)Amino)Ethyl Ester, p-Oxide is a specialized organophosphorus compound containing both sulfonic acid and cyclic phosphoramidate ester functionalities. This unique structure makes it a valuable intermediate for the synthesis of advanced materials and biologically active molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, leveraging its phosphoramidate moiety.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to impart sulfonic acid groups and specific reactivity into specialty polymers.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create complex ligands for catalytic systems.
• Surface Functionalization: Used to modify material surfaces for enhanced hydrophilicity, adhesion, or specific binding properties.
• Chemical Biology Research: A tool compound for probing enzyme activity or designing activity-based probes targeting specific phosphatases or related enzymes.

Basic Information

Product Name	1-Propanesulfonic Acid, 2-((3-(2-Chloroethyl)Tetrahydro-2H-1,3,2-Oxaza Phosphorin-2-Yl)Amino)Ethyl Ester, p-Oxide
CAS No.	37752-41-3
Molecular Formula	C10H22ClN2O6PS
Molecular Weight	380.78 g/mol
Synonyms	2-[(3-(2-Chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amino]ethyl 1-propanesulfonate; 2-((3-(2-Chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-yl)amino)ethyl propane-1-sulfonate oxide; Cyclophosphamide Impurity; Cyclophosphamide Related Compound; Phosphoramide mustard propanesulfonate ester; NSC 26271; Propanesulfonic acid cyclic phosphoramidate ester
EINECS	Contact for details

Quality Control

Our production of 1-Propanesulfonic Acid, 2-((3-(2-Chloroethyl)Tetrahydro-2H-1,3,2-Oxaza Phosphorin-2-Yl)Amino)Ethyl Ester, p-Oxide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We comply with relevant Good Manufacturing Practice (GMP) principles for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.