Description

Ethanol, 2-((3-Ethyltetrahydro-2H-1,3,2-oxazaphosphorin-2-yl)amino)-, methanesulfonate (ester), p-oxide is a specialized organophosphorus compound of significant interest in advanced chemical synthesis and pharmaceutical research. This high-purity intermediate is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and industrial manufacturers engaged in the synthesis of phosphoramidate and related compounds for therapeutic and agrochemical applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel phosphoramidate prodrugs and nucleotide analogs with potential antiviral or anticancer activity.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its phosphorus-containing heterocyclic structure.
• Chemical Synthesis: Serves as a versatile intermediate for constructing complex heterocycles and functionalized molecules in advanced organic chemistry.
• Bioconjugation & Prodrug Design: Employed in the design of targeted drug delivery systems where its reactive groups facilitate linkage to biomolecules or masking of active drug moieties.
• Material Science Research: Investigated as a precursor for specialty polymers or functional materials requiring phosphorus-based modifiers.
• Academic & R&D Laboratories: Utilized as a reference standard and reagent in methodological studies and discovery chemistry within universities and corporate R&D centers.

Basic Information

Product Name	Ethanol, 2-((3-Ethyltetrahydro-2H-1,3,2-oxazaphosphorin-2-yl)amino)-, methanesulfonate (ester), p-oxide
CAS No.	37752-40-2
Molecular Formula	C8H19N2O5PS
Molecular Weight	286.28 g/mol
Synonyms	2-((3-Ethyltetrahydro-2H-1,3,2-oxazaphosphorin-2-yl)amino)ethyl methanesulfonate P-oxide; 2-(3-Ethyl-1,3,2-oxazaphosphinan-2-ylamino)ethyl methanesulfonate 2-oxide; Cyclophosphamide Impurity; Cyclophosphamide Related Compound; N-(2-(Methanesulfonyloxy)ethyl)-3-ethyl-1,3,2-oxazaphosphinan-2-amine 2-oxide; Phosphoramide mustard precursor; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research and manufacturing processes. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Quality assurance is guided by ICH guidelines and current Good Manufacturing Practice (cGMP) principles where applicable, ensuring the material meets the exacting standards required for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.