Description

Methyl 7-Hydroxy-5-Oxo-1,2,3,5-Tetrahydroindolizine-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused indolizine core structure. This compound is of significant commercial value for its role as a key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of complex heterocyclic drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• API Synthesis: A key precursor in the multi-step manufacturing processes of potential pharmaceuticals targeting various diseases.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in R&D laboratories.
• Academic Research: Utilized in university and institutional research exploring novel organic synthesis methodologies and heterocyclic chemistry.

Basic Information

Product Name	Methyl 7-Hydroxy-5-Oxo-1,2,3,5-Tetrahydroindolizine-8-Carboxylate
CAS No.	37704-45-3
Molecular Formula	C11H11NO4
Molecular Weight	221.21 g/mol
Synonyms	Methyl 7-hydroxy-5-oxo-2,3-dihydro-1H-pyrrolizine-8-carboxylate; 8-Carbomethoxy-7-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine; 7-Hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid methyl ester; 1,2,3,5-Tetrahydro-7-hydroxy-5-oxoindolizine-8-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 7-Hydroxy-5-Oxo-1,2,3,5-Tetrahydroindolizine-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.