Description

Diethyl 1H-Pyrazole-4,5-Dicarboxylate is a versatile heterocyclic building block and key synthetic intermediate in organic chemistry. Its value lies in the functionalized pyrazole core, which is a privileged scaffold for constructing more complex molecules with targeted biological or material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyrazole moiety for enhanced bioactivity and selectivity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with specific electronic or optical properties.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse R&D projects.

Basic Information

Product Name	Diethyl 1H-Pyrazole-4,5-Dicarboxylate
CAS No.	37687-26-6
Molecular Formula	C9H12N2O4
Molecular Weight	212.20 g/mol
Synonyms	1H-Pyrazole-4,5-dicarboxylic acid, diethyl ester; Diethyl pyrazole-4,5-dicarboxylate; 4,5-Pyrazoledicarboxylic acid diethyl ester; Ethyl 4,5-pyrazoledicarboxylate; Diethyl 4,5-pyrazoledicarboxylate; 1H-Pyrazole-4,5-dicarboxylic acid 4,5-diethyl ester; 37687-26-6
EINECS	Contact for details

Quality Control

Our Diethyl 1H-Pyrazole-4,5-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.