Description

2-(Bromomethyl)-5-Fluoro-2,3-Dihydrobenzofuran is a versatile and high-value halogenated benzofuran derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a fluorine substituent, makes it an essential intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients. Its utility extends to materials science for the development of specialty polymers and functionalized organic frameworks.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of fluorinated organic semiconductors, liquid crystals, and photoactive materials.
• Chemical Biology Probe Synthesis: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A starting material for custom synthesis projects requiring functionalized dihydrobenzofuran scaffolds.

Basic Information

Product Name	2-(Bromomethyl)-5-Fluoro-2,3-Dihydrobenzofuran
CAS No.	37603-11-5
Molecular Formula	C9H8BrFO
Molecular Weight	231.06 g/mol
Synonyms	5-Fluoro-2-(bromomethyl)-2,3-dihydrobenzofuran; 2,3-Dihydro-5-fluoro-2-(bromomethyl)benzofuran; 5-Fluoro-2-(bromomethyl)-2,3-dihydro-1-benzofuran; 2-(Bromomethyl)-5-fluoro-2,3-dihydro-1-benzofuran; 37603-11-5; 5-Fluoro-2-bromomethyl-2,3-dihydrobenzofuran
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-5-Fluoro-2,3-Dihydrobenzofuran is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing all critical specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.