Description

Ethyl 3-Amino-5-(4-Methylphenyl)Thiophene-2-Carboxylate is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of pharmaceuticals and specialty chemicals. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for their synthetic pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the thiophene core for bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating specialized heterocyclic dyes and organic pigments.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces in medicinal chemistry.
• Custom Synthesis: A starting point for the contract manufacturing of bespoke, complex organic molecules for various industrial applications.

Basic Information

Item	Detail
Product Name	Ethyl 3-Amino-5-(4-Methylphenyl)Thiophene-2-Carboxylate
CAS No.	37572-22-8
Molecular Formula	C14H15NO2S
Molecular Weight	261.34 g/mol
Synonyms	Ethyl 3-Amino-5-p-tolylthiophene-2-carboxylate; 3-Amino-5-(4-methylphenyl)thiophene-2-carboxylic Acid Ethyl Ester; 2-Thiophenecarboxylic acid, 3-amino-5-(4-methylphenyl)-, ethyl ester; 5-(4-Methylphenyl)-3-aminothiophene-2-carboxylic acid ethyl ester; ATEC; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Amino-5-(4-Methylphenyl)Thiophene-2-Carboxylate is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive testing includes identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) documenting all test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.