Description

(R)-4-Benzyl-Oxazolidine-2,5-Dione is a high-purity chiral oxazolidinedione derivative, a crucial building block in asymmetric synthesis and pharmaceutical development. Its enantiomerically pure structure makes it an invaluable intermediate for constructing complex molecules with defined stereochemistry. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalysis: Used as a precursor or auxiliary in the development of chiral catalysts and ligands for stereoselective reactions.
• Agrochemical Research: Serves as a building block for creating novel, optically active pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring high stereochemical fidelity.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and stereochemistry research at universities and corporate R&D centers.
• Peptidomimetics: Acts as a constrained scaffold or turn inducer in the design and synthesis of peptide mimics for drug discovery.

Basic Information

Product Name	(R)-4-Benzyl-Oxazolidine-2,5-Dione
CAS No.	37498-95-6
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	(R)-4-Benzyl-2-oxazolidinone; (R)-(-)-4-Benzyl-2-oxazolidinone; (R)-4-Benzyloxazolidin-2-one; (R)-N-Benzyloxazolidinone; (R)-BOZ; (R)-4-Benzyl-1,3-oxazolidine-2,5-dione; (R)-4-Benzyl-2-oxo-1,3-oxazolidine-5-one; (R)-4-Phenylmethyl-2-oxazolidinone
EINECS	Contact for details

Quality Control

Our (R)-4-Benzyl-Oxazolidine-2,5-Dione is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure consistent high quality and enantiomeric excess (e.e.) suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (e.e.)	≥ 99.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.