Description

Methyl 1-Chloro-4-Isoquinolinecarboxylate is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold's bioactivity.
• Organic Synthesis Building Block: Serves as a versatile substrate for further functionalization, including cross-coupling reactions, nucleophilic substitutions, and cyclizations.
• Material Science Research: Investigated for the creation of organic semiconductors, ligands for catalysts, and advanced polymers with specific electronic or optical properties.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodological studies in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Methyl 1-Chloro-4-Isoquinolinecarboxylate
CAS No.	37497-86-2
Molecular Formula	C11H8ClNO2
Molecular Weight	221.64 g/mol
Synonyms	1-Chloro-4-isoquinolinecarboxylic acid methyl ester; Methyl 1-chloroisoquinoline-4-carboxylate; 1-Chloro-4-(methoxycarbonyl)isoquinoline; 4-(Methoxycarbonyl)-1-chloroisoquinoline; 1-Chloro-4-carbomethoxyisoquinoline; Isoquinoline-4-carboxylic acid, 1-chloro-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 1-Chloro-4-Isoquinolinecarboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.