Description

(R)-(-)-2-Chloropropan-1-Ol CAS NO 37493-14-4 is a chiral building block of significant importance in asymmetric synthesis. This optically active chlorohydrin serves as a versatile intermediate for constructing complex molecules with defined stereochemistry. It is primarily sought after by pharmaceutical, agrochemical, and fine chemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of β-blockers, antiviral agents, and other therapeutic compounds.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators where specific stereochemistry is crucial for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Manufacturing: Employed in the synthesis of specialty chemicals, flavors, and fragrances that require enantiomerically pure components.
• Academic and R&D: Utilized in research laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(R)-(-)-2-Chloropropan-1-Ol
CAS No.	37493-14-4
Molecular Formula	C3H7ClO
Molecular Weight	94.54 g/mol
Synonyms	(R)-2-Chloro-1-propanol; (R)-(-)-2-Chloropropanol; (R)-2-Chloropropan-1-ol; (R)-1-Chloro-2-propanol; (R)-2-Chloro-1-hydroxypropane; (R)-α-Chloroisopropyl alcohol; (R)-(-)-2-Chloro-1-propanol; (R)-2-Chloropropyl alcohol
EINECS	Contact for details

Quality Control

Our (R)-(-)-2-Chloropropan-1-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) determination by chiral GC or HPLC, chemical assay, and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.