Description

Isoquinoline, 1,2,3,4-Tetrahydro-5-(2,6-Diethylbenzamido)-2-Methyl- is a high-purity, synthetically derived organic compound belonging to the tetrahydroisoquinoline class, serving as a critical advanced intermediate for pharmaceutical research and development. Its molecular architecture makes it a valuable scaffold for medicinal chemists targeting specific biological pathways. This compound is essential for organizations engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly within the fields of central nervous system (CNS) and cardiovascular drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, especially those with tetrahydroisoquinoline cores.
• Medicinal Chemistry Research: Used as a privileged scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• API Development: Serves as a precursor in the development of advanced active pharmaceutical ingredients (APIs) for preclinical and clinical trials.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery pipelines for global pharmaceutical companies.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	Isoquinoline, 1,2,3,4-Tetrahydro-5-(2,6-Diethylbenzamido)-2-Methyl-
CAS No.	37481-42-8
Molecular Formula	C21H28N2O
Molecular Weight	324.46 g/mol
Synonyms	5-[(2,6-Diethylbenzoyl)amino]-2-methyl-1,2,3,4-tetrahydroisoquinoline; 2-Methyl-5-(2,6-diethylbenzamido)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-2-methyl-5-[(2,6-diethylbenzoyl)amino]isoquinoline; N-(2,6-Diethylphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline-5-carboxamide; Tetrahydroisoquinoline derivative 37481-42-8
EINECS	Contact for details

Quality Control

Our Isoquinoline, 1,2,3,4-Tetrahydro-5-(2,6-Diethylbenzamido)-2-Methyl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.