Description

3,4-Dimethoxy-n-(1,2,3,4-Tetrahydro-2-Propylisoquinolin-5-Yl)Benzamide is a specialized organic compound belonging to the isoquinoline class, serving as a key intermediate in advanced pharmaceutical synthesis. Its molecular structure makes it a valuable building block for research and development in medicinal chemistry, particularly for creating novel therapeutic agents. This high-purity intermediate is essential for pharmaceutical manufacturers and R&D laboratories focused on developing new drug candidates targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules with targeted biological activity.
• Biochemical Research: Employed as a reference standard or probe compound in pharmacological assays to study receptor interactions and enzyme inhibition.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for exploratory synthetic chemistry and drug discovery programs.

Basic Information

Item	Detail
Product Name	3,4-Dimethoxy-n-(1,2,3,4-Tetrahydro-2-Propylisoquinolin-5-Yl)Benzamide
CAS No.	37481-32-6
Molecular Formula	C21H26N2O3
Molecular Weight	354.45 g/mol
Synonyms	5-[(3,4-Dimethoxybenzoyl)amino]-2-propyl-1,2,3,4-tetrahydroisoquinoline; 2-Propyl-5-[(3,4-dimethoxybenzoyl)amino]-1,2,3,4-tetrahydroisoquinoline; N-(1,2,3,4-Tetrahydro-2-propyl-5-isoquinolinyl)-3,4-dimethoxybenzamide; Benzamide, 3,4-dimethoxy-N-(1,2,3,4-tetrahydro-2-propyl-5-isoquinolinyl)-; 37481-32-6; 3,4-Dimethoxy-N-(2-propyl-1,2,3,4-tetrahydroisoquinolin-5-yl)benzamide
EINECS	Contact for details

Quality Control

Our 3,4-Dimethoxy-n-(1,2,3,4-Tetrahydro-2-Propylisoquinolin-5-Yl)Benzamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality system is designed to support regulatory submissions, and we can supply material that meets the stringent requirements for cGMP starting materials upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.