Description

Isoquinoline, 1,2,3,4-Tetrahydro-5-(4-Methoxybenzamido)-, Hydrochloride is a high-purity, specialized organic compound belonging to the tetrahydroisoquinoline class, serving as a critical synthetic intermediate and research chemical. Its value lies in its role as a versatile building block for the development of novel pharmacologically active molecules, particularly in central nervous system (CNS) and cardiovascular research. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds and potential drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential therapeutic agents targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Biochemical Tool Compound: Employed in in vitro and in vivo studies to investigate specific biological mechanisms and receptor interactions.
• Fine Chemical Synthesis: Serves as a building block for creating complex, multi-functional organic molecules in advanced synthetic chemistry.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental chemical and pharmacological research.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	Isoquinoline, 1,2,3,4-Tetrahydro-5-(4-Methoxybenzamido)-, Hydrochloride
CAS No.	37481-27-9
Molecular Formula	C17H19ClN2O2
Molecular Weight	318.80 g/mol
Synonyms	5-[(4-Methoxybenzoyl)amino]-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-5-[(4-methoxybenzoyl)amino]isoquinoline hydrochloride; 4-Methoxy-N-(1,2,3,4-tetrahydro-5-isoquinolinyl)benzamide hydrochloride; 5-(4-Methoxybenzamido)-1,2,3,4-tetrahydroisoquinoline HCl; N-(1,2,3,4-Tetrahydroisoquinolin-5-yl)-4-methoxybenzamide hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with research-grade standards. Identity, purity, and impurity profiles are verified using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.