Description

(E)-3-Iodo-2-Buten-1-Ol is a versatile halogenated allylic alcohol building block of significant interest in synthetic organic chemistry. Its unique structure, featuring both an iodine atom and a hydroxyl group on an alkene backbone, makes it a valuable precursor for cross-coupling reactions and the synthesis of complex molecules. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly in constructing complex heterocycles and bioactive molecules via Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the iodine moiety allows for efficient functionalization to create targeted bioactive compounds.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands or organocatalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the creation of functionalized polymers or organic electronic materials, where the reactive sites enable precise molecular engineering.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis, exploring new reaction pathways involving halogenated olefins.

Basic Information

Product Name	(E)-3-Iodo-2-Buten-1-Ol
CAS No.	37428-58-3
Molecular Formula	C4H7IO
Molecular Weight	198.00 g/mol
Synonyms	(E)-3-Iodo-2-buten-1-ol; (E)-3-Iodobut-2-en-1-ol; trans-3-Iodo-2-buten-1-ol; 3-Iodo-2-buten-1-ol, (E)-; 1-Buten-1-ol, 3-iodo-, (E)-; 3-Iodobut-2-en-1-ol; Halogenated allylic alcohol; Iodinated butenol
EINECS	Contact for details

Quality Control

Every batch of (E)-3-Iodo-2-Buten-1-Ol is produced and tested under strict quality management protocols to ensure consistency and reliability for research and scale-up applications. Our standard grade meets high-purity specifications suitable for synthetic chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support custom synthesis and can tailor purity grades to meet specific project requirements, including compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.