Description

Apramycin is a broad-spectrum aminoglycoside antibiotic derived from *Streptomyces tenebrarius*, widely recognized for its efficacy against Gram-negative bacteria. Its primary commercial value lies in its potent activity against bacterial pathogens that have developed resistance to other aminocyclitol antibiotics, making it a critical tool in specific therapeutic areas. This compound is essential for manufacturers in the veterinary pharmaceutical and animal health sectors, where it is formulated to treat gastrointestinal infections in livestock and poultry.

Application

• Veterinary Medicine: Primary use in oral solutions and premixes for the treatment and control of colibacillosis and salmonellosis in swine, cattle, and poultry.
• Aquaculture: Used in medicated feeds to combat bacterial infections in farmed fish and shrimp.
• Research & Development: Serves as a key reference standard and active ingredient in microbiological and pharmacological research.
• Pharmaceutical Intermediates: Acts as a starting material or intermediate in the synthesis of more complex antibiotic derivatives.
• Feed Additives: Incorporated into animal feed at approved levels for disease prevention and growth promotion under veterinary guidance.

Basic Information

Product Name	Apramycin
CAS No.	37321-09-8
Molecular Formula	C21H41N5O11
Molecular Weight	539.58 g/mol
Synonyms	Apramycin Sulfate; Nebramycin II; APR; 4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-β-D-ribofuranosyl-2-deoxystreptamine; Antibiotic 44729; EL-857/820; Apramycine; Apramycinum
EINECS	253-451-2

Quality Control

Our Apramycin is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including HPLC for purity and potency, specific tests for related substances, and microbiological assays. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Retention time corresponds to reference standard
Assay (on dried basis)	≥ 95.0% (by HPLC)
Water Content (KF)	≤ 5.0%
pH (1% solution)	5.0 - 7.5
Residue on Ignition	≤ 1.0%
Specific Rotation	+154° to +164° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.