Description

(20α)-3β,21β-Epoxy-17β,19β-Dimethoxy-21A-Homo-18-Oxayohimban CAS NO 37304-95-3 is a complex, high-purity alkaloid derivative belonging to the yohimbane class. This compound is valued as a critical advanced pharmaceutical intermediate and a versatile research-grade building block for the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams, contract research organizations (CROs), and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic agents targeting neurological and cardiovascular systems.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating alkaloid biosynthesis pathways and enzyme interactions.
• Organic Synthesis: A valuable chiral building block for constructing complex polycyclic frameworks in advanced synthetic chemistry.

Basic Information

Product Name	(20α)-3β,21β-Epoxy-17β,19β-Dimethoxy-21A-Homo-18-Oxayohimban
CAS No.	37304-95-3
Molecular Formula	C23H28N2O4
Molecular Weight	396.48 g/mol
Synonyms	21A-Homo-18-oxayohimban-3β,21β-epoxy-17β,19β-dimethoxy; 3β,21β-Epoxy-17β,19β-dimethoxy-21a-homo-18-oxayohimban; 17β,19β-Dimethoxy-3β,21β-epoxy-21a-homo-18-oxayohimban; Yohimbane alkaloid derivative; Oxayohimban derivative; 37304-95-3; (20α)-3β,21β-Epoxy-17β,19β-dimethoxy-21a-homo-18-oxayohimban
EINECS	Contact for details

Quality Control

Our (20α)-3β,21β-Epoxy-17β,19β-Dimethoxy-21A-Homo-18-Oxayohimban is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.