Description

O,o-Bis(Trimethylsilyl)Azadirachtin is a chemically modified, silylated derivative of the potent natural insect growth regulator azadirachtin, designed to enhance stability and handling properties. This derivative is critical for research and development in advanced agrochemical formulations, offering a more lipophilic and protected form of the active compound. It is primarily utilized by agrochemical researchers, process chemists, and manufacturers developing next-generation, environmentally benign botanical pesticides and insect growth regulators.

Application

• Agrochemical Intermediate: A key synthetic intermediate for the production of novel, stabilized azadirachtin analogs with improved field persistence.
• Research & Development: Used in academic and industrial R&D for studying structure-activity relationships (SAR) of modified limonoids.
• Reference Standard: Serves as an analytical standard for quality control and method development in the analysis of azadirachtin-based products.
• Formulation Development: Employed in creating experimental pesticide formulations with enhanced solubility in organic carriers or controlled-release matrices.
• Biochemical Studies: Utilized in mechanistic studies to understand the bioavailability and metabolic pathways of modified botanical actives.

Basic Information

Product Name	O,o-Bis(Trimethylsilyl)Azadirachtin
CAS No.	37293-15-5
Molecular Formula	C41H63NO15Si2
Molecular Weight	866.19 g/mol
Synonyms	Azadirachtin, O,O-bis(trimethylsilyl) derivative; Bis(trimethylsilyl) Azadirachtin; Azadirachtin TMS derivative; 3-Tigloylazadirachtol O,O-bis(trimethylsilyl) ether; 22,23-Dihydroazadirachtin O,O-bis(trimethylsilyl) ether (related derivative); Botanical Insecticide Intermediate; Silylated Azadirachtin
EINECS	Contact for details

Quality Control

Our O,o-Bis(Trimethylsilyl)Azadirachtin is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While not a pharmacopeial material, quality is assured against in-house specifications developed for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.