Description

2-Chloro-8-Fluoro-10-Hydroxy-10H-Phenoxaphosphine 10-Oxide is a specialized organophosphorus compound with a unique phenoxaphosphine oxide core structure. This high-purity intermediate is critical for advanced research and development in pharmaceutical and agrochemical synthesis, where its distinct halogenated and hydroxylated framework enables the construction of complex molecules. It is primarily sought after by R&D chemists and process development scientists in fine chemical, pharmaceutical, and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with enhanced activity profiles.
• Ligand Precursor: Serves as a sophisticated precursor for chiral or bidentate ligands in asymmetric catalysis and metal complexation.
• Material Science Research: Investigated for incorporation into specialty polymers, flame retardants, or electronic materials due to its phosphorus-containing heterocyclic structure.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying phosphoprotein interactions and signaling pathways.

Basic Information

Product Name	2-Chloro-8-Fluoro-10-Hydroxy-10H-Phenoxaphosphine 10-Oxide
CAS No.	37041-11-5
Molecular Formula	C₁₂H₇ClFO₂P
Molecular Weight	283.61 g/mol
Synonyms	10H-Phenoxaphosphine 10-oxide, 2-chloro-8-fluoro-10-hydroxy-; 2-Chloro-8-fluoro-10-hydroxy-10H-phenoxaphosphine 10-oxide; 2-Chloro-8-fluorophenoxaphosphine-10-ol 10-oxide; Phenoxaphosphine oxide derivative; 37041-11-5; CAS 37041-11-5
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-8-Fluoro-10-Hydroxy-10H-Phenoxaphosphine 10-Oxide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.