Description

α-(Phenylmethylene)-2-Thiopheneacetonitrile is a versatile organic intermediate featuring a thiophene core linked to a benzylic nitrile group. This compound matters for its role as a key building block in the synthesis of complex heterocyclic molecules and active pharmaceutical ingredients (APIs). It is needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science Research: Acts as a monomer or building block for creating specialized polymers and organic electronic materials due to the conjugated thiophene system.
• Chemical Research & Development: Employed in organic synthesis laboratories for constructing complex molecular architectures, including fused-ring systems and functionalized heterocycles.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal catalysis and coordination chemistry applications.

Basic Information

Product Name	α-(Phenylmethylene)-2-Thiopheneacetonitrile
CAS No.	37033-97-9
Molecular Formula	C13H9NS
Molecular Weight	211.28 g/mol
Synonyms	2-[(Phenylmethylene)thiophen-2-yl]acetonitrile; (2-Thienyl)(phenyl)acrylonitrile; 2-[(Phenylmethylidene)-2-thienyl]acetonitrile; α-Benzylidene-2-thiopheneacetonitrile; (E/Z)-2-((Phenylmethylene)(thiophen-2-yl))acetonitrile; 2-Thiopheneacetonitrile, α-(phenylmethylene)-; α-(Phenylmethylidene)-2-thiopheneacetonitrile
EINECS	Contact for details

Quality Control

Our α-(Phenylmethylene)-2-Thiopheneacetonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.