Description

3,4-Dibromoisoquinoline is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its dual reactive bromine sites, which enable selective functionalization for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel isoquinoline-based drug candidates, including potential kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold's bioactivity.
• Ligand Synthesis: Acts as a starting material for the preparation of specialized nitrogen-containing ligands used in catalysis and material science.
• Functional Material Development: Employed in the creation of organic electronic materials, such as charge-transport layers or light-emitting components, due to its electron-deficient aromatic system.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, or Buchwald-Hartwig amination, allowing for diverse carbon-carbon and carbon-heteroatom bond formations.
• Chemical Library Construction: Utilized in parallel and combinatorial synthesis within medicinal chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Item	Detail
Product Name	3,4-Dibromoisoquinoline
CAS No.	36963-44-7
Molecular Formula	C9H5Br2N
Molecular Weight	286.95 g/mol
Synonyms	3,4-Dibromo-isoquinoline; Isoquinoline, 3,4-dibromo-; 3,4-Dibromoisoquinolin; 36963-44-7; AI3-52642; CTK8G7235; NSC 403697; STL283910
EINECS	Contact for details

Quality Control

Our 3,4-Dibromoisoquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.