Description

1-(4-Bromo-5-Methyl-Thiophen-2-Yl)-Ethanone is a high-purity brominated thiophene derivative, a crucial building block in advanced organic synthesis. Its value lies in its reactive ketone and halogenated aromatic structure, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring complex thiophene-based heterocycles.
• Agrochemical Synthesis: Serves as a critical precursor in the manufacture of advanced pesticides, herbicides, and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Used in the synthesis of organic semiconductors, conductive polymers, and other functional materials where thiophene units are integral.
• Organic Synthesis Building Block: Facilitates various cross-coupling reactions (e.g., Suzuki, Stille) and further functionalization due to the presence of the bromine atom and acetyl group.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal catalysis and organocatalysts.
• Dye and Pigment Intermediate: Acts as a precursor in the synthesis of specialized dyes and pigments containing thiophene rings.

Basic Information

Product Name	1-(4-Bromo-5-Methyl-Thiophen-2-Yl)-Ethanone
CAS No.	36901-17-4
Molecular Formula	C7H7BrOS
Molecular Weight	219.10 g/mol
Synonyms	2-Acetyl-4-bromo-5-methylthiophene; 4-Bromo-5-methyl-2-acetylthiophene; 1-(4-Bromo-5-methyl-2-thienyl)ethanone; 4-Bromo-5-methylthiophene-2-yl methyl ketone; Ethanone, 1-(4-bromo-5-methyl-2-thienyl)-; 36901-17-4; 2-Thiophenecarboxylic acid, 4-bromo-5-methyl-, methyl ester (related); Bromo-methyl acetyl thiophene
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-5-Methyl-Thiophen-2-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.