Description

5-Oxaproline is a versatile heterocyclic building block and key intermediate in organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and bioactive compounds. Industries such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical synthesis need this high-purity intermediate for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of protease inhibitors, peptidomimetics, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Serves as a constrained proline analog or a specialty amino acid derivative in peptide-based drug discovery.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or functional additive for designing polymers with specific properties.
• Bioconjugation and Probe Synthesis: Utilized in the preparation of chemical probes and bioconjugates for biochemical and diagnostic applications.

Basic Information

Product Name	5-Oxaproline
CAS No.	36839-09-5
Molecular Formula	C4H5NO2
Molecular Weight	99.09 g/mol
Synonyms	5-Oxaproline; 2,5-Dihydro-1,2-oxazole-5-carboxylic acid; 5-Oxazoline-5-carboxylic acid; 3,4-Dihydro-2H-1,2-oxazole-5-carboxylic acid; Isoxazolidine-5-carboxylic acid; 1,2-Oxazolidine-5-carboxylic acid; 5-Oxazolidinecarboxylic acid; 36839-09-5
EINECS	Contact for details

Quality Control

Our 5-Oxaproline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.