Description

4-Chlorobenzo[4,5]Thieno[3,2-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the heterocyclic compound class. This compound is a critical building block in the synthesis of complex molecules, particularly for active pharmaceutical ingredients (APIs) targeting various therapeutic areas. It is essential for research and development chemists, process scale-up specialists, and manufacturers in the pharmaceutical and agrochemical industries seeking reliable, high-quality raw materials for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core structure.
• Material Science Research: Serves as a building block for organic electronic materials and specialty polymers.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development studies in university and CRO laboratories.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	4-Chlorobenzo[4,5]Thieno[3,2-D]Pyrimidine
CAS No.	36822-09-0
Molecular Formula	C10H5ClN2S
Molecular Weight	220.68 g/mol
Synonyms	4-Chlorobenzo[4,5]thieno[3,2-d]pyrimidine; 4-Chloro-benzo[4,5]thieno[3,2-d]pyrimidine; 4-Chlorobenzo(4,5)thieno(3,2-d)pyrimidine; Benzo[4,5]thieno[3,2-d]pyrimidine, 4-chloro-; 36822-09-0; 4-Chloro-benzo[4,5]thieno[3,2-d]pyrimidine; 4-Chloro-benzo(4,5)thieno(3,2-d)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chlorobenzo[4,5]Thieno[3,2-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of material suitable for demanding pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.