Description

5-(2-Chlorophenyl)-1,3-Dihydro-2H-Thieno(2,3-E)(1,4)Diazepin-2-One is a high-purity, specialized heterocyclic compound that serves as a critical building block in advanced pharmaceutical research and development. Its unique fused-ring structure containing diazepine and thiophene moieties makes it a valuable intermediate for synthesizing novel active pharmaceutical ingredients (APIs) and bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical companies focused on developing new therapeutic agents, particularly in the fields of central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel benzodiazepine and thienodiazepine analogs for potential therapeutic applications.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the complex multi-step synthesis of target molecules for preclinical and clinical studies.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize pharmacological properties.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Investigated for its interaction with various biological targets, including GABA receptors and other neurological pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	5-(2-Chlorophenyl)-1,3-Dihydro-2H-Thieno(2,3-E)(1,4)Diazepin-2-One
CAS No.	36811-58-2
Molecular Formula	C13H9ClN2OS
Molecular Weight	276.74 g/mol
Synonyms	5-(2-Chlorophenyl)-1,3-dihydro-2H-thieno[2,3-e][1,4]diazepin-2-one; 2H-Thieno[2,3-e][1,4]diazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-; 5-(o-Chlorophenyl)-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one; Thienodiazepinone derivative; 36811-58-2; 5-(2-Chlorophenyl)thienodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 5-(2-Chlorophenyl)-1,3-Dihydro-2H-Thieno(2,3-E)(1,4)Diazepin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We can supply material compliant with research-grade specifications and support development toward cGMP standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.