Description

1-Methyl-3-Nitro-1H-Indole is a versatile nitro-substituted indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized scaffold for constructing complex molecules, particularly in the synthesis of pharmaceuticals and agrochemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or fine-tune molecular properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of new pesticides, herbicides, and fungicides, leveraging the indole core for biological activity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, due to its electron-deficient nitro group.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and pigments, where the nitro-indole structure contributes to color properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in heterocyclic and medicinal chemistry.
• Fine Chemical Production: Utilized in custom synthesis and scale-up projects for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	1-Methyl-3-Nitro-1H-Indole
CAS No.	36728-89-9
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	3-Nitro-1-methylindole; 1-Methyl-3-nitroindole; 3-Nitro-1-methyl-1H-indole; 1H-Indole, 1-methyl-3-nitro-; N-Methyl-3-nitroindole; 1-Methyl-3-nitroindole; 3-Nitro-N-methylindole; Methyl 3-nitroindole
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-Nitro-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment. We can support development projects with custom purity grades and specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nitro-substituted structure, it should be stored separately from strong reducing agents and bases.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.