Description

9-[3-(Dimethylamino)Propyl]-2-[(4-Methoxybenzyl)Oxy]-9H-Thioxanthen-9-Ol is a specialized thioxanthene derivative, a key advanced pharmaceutical intermediate of significant interest in modern synthetic chemistry. This compound matters for its role as a crucial building block in the development of novel therapeutic agents, particularly within the central nervous system (CNS) drug discovery pipeline. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to synthesize potential antipsychotic and neuroleptic drug candidates, enabling critical structure-activity relationship (SAR) studies and process development.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor in the research and development of novel thioxanthene-based antipsychotic medications.
• Neurological Drug Discovery: Serves as a core scaffold for creating new chemical entities (NCEs) targeting dopamine and serotonin receptors for CNS disorders.
• Process Chemistry & Scale-Up: Used in optimizing synthetic routes and manufacturing processes for active pharmaceutical ingredients (APIs) in late-stage development.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related drug substances.
• Academic & Contract Research: Utilized in university and CRO settings for pharmacological studies and medicinal chemistry research programs.
• Custom Synthesis: A starting material for the custom synthesis of structurally modified analogs for proprietary drug discovery projects.

Basic Information

Item	Details
Product Name	9-[3-(Dimethylamino)Propyl]-2-[(4-Methoxybenzyl)Oxy]-9H-Thioxanthen-9-Ol
CAS No.	36685-63-9
Molecular Formula	C26H29NO3S
Molecular Weight	435.58 g/mol
Synonyms	2-[(4-Methoxybenzyl)oxy]-9-[3-(dimethylamino)propyl]thioxanthen-9-ol; 9-[3-(Dimethylamino)propyl]-2-[(4-methoxybenzyl)oxy]-9H-thioxanthen-9-ol; Thioxanthen-9-ol derivative; N-Methylspiperone intermediate; Potential Flupentixol/Zuclopenthixol precursor; CNS active intermediate; Dimethylaminopropyl thioxanthenol derivative
EINECS	Contact for details

Quality Control

Every batch of 9-[3-(Dimethylamino)Propyl]-2-[(4-Methoxybenzyl)Oxy]-9H-Thioxanthen-9-Ol is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure identity, purity, and consistency that meet the exacting standards of pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.