Description

1,4-Butane-1,1,4,4-D4-Diol is a deuterium-labeled analog of 1,4-butanediol, where four hydrogen atoms are replaced with the stable isotope deuterium. This compound is a critical tool in advanced research and development, enabling precise mechanistic studies and metabolic pathway analysis through mass spectrometry and NMR spectroscopy. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications requiring isotopic labeling.

Application

• Pharmaceutical Research & Development: As an internal standard or tracer in quantitative mass spectrometry for pharmacokinetic and metabolic studies.
• Deuterated Polymer Synthesis: Used as a monomer for creating deuterated polyurethanes, polyesters, and other specialty polymers with modified physical properties for research.
• Analytical Chemistry: Serves as a high-purity reference standard for calibrating analytical instruments and validating methods in complex matrices.
• Organic Synthesis: Acts as a deuterium-labeled building block for synthesizing more complex deuterated intermediates and active pharmaceutical ingredients (APIs).
• NMR Spectroscopy Solvent & Reagent: Employed in the preparation of deuterated solvents or as a probe molecule in nuclear magnetic resonance studies.
• Agrochemical Research: Used in environmental fate studies and metabolism research of agricultural chemicals to track molecular pathways.

Basic Information

Product Name	1,4-Butane-1,1,4,4-D4-Diol
CAS No.	36684-44-3
Molecular Formula	C4D4H6O2
Molecular Weight	94.13 g/mol
Synonyms	1,4-Butanediol-d4; [1,1,4,4-2H4]-1,4-Butanediol; Tetradeuterated 1,4-Butanediol; 1,1,4,4-Tetradeutero-1,4-butanediol; BDO-d4; Butane-1,4-diol-d4; 1,4-BD-d4; Deuterated 1,4-Butylene Glycol
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced under strict quality management systems. Each batch of 1,4-Butane-1,1,4,4-D4-Diol undergoes rigorous analytical testing, including NMR and GC/MS, to confirm isotopic enrichment, chemical purity, and identity. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic purity, and impurities are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.