Description

5-Methyl-8-Hydroxycoumarin is a substituted coumarin derivative, a versatile organic intermediate prized for its unique photophysical and biological properties. This compound matters for its role as a key building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs). Industries such as fine chemicals, pharmaceutical R&D, and material science require this high-purity intermediate for developing novel compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those exploring anticoagulant or fluorescent probe activities.
• Organic Light-Emitting Diodes (OLEDs): Used in the development of electron-transport materials or host materials due to the coumarin scaffold's favorable photoluminescent properties.
• Fluorescent Dyes and Probes: Acts as a core structure for creating sensitive fluorescent sensors and biological staining agents, leveraging its hydroxy and methyl substituents for functionalization.
• Fine Chemical Synthesis: Employed as a specialized building block for constructing complex organic molecules in research and industrial-scale chemical production.
• Cosmetic Ingredient Research: Investigated for potential use in sunscreen formulations or skincare products due to the UV-absorbing characteristics of the coumarin moiety.
• Agrochemical Intermediate: Utilized in the research and development of new pesticides or plant growth regulators.

Basic Information

Product Name	5-Methyl-8-Hydroxycoumarin
CAS No.	36651-81-7
Molecular Formula	C10H8O3
Molecular Weight	176.17 g/mol
Synonyms	8-Hydroxy-5-methylcoumarin; 5-Methylumbelliferone; 5-Methyl-8-hydroxy-2H-chromen-2-one; 5-Methyl-8-hydroxy-2H-1-benzopyran-2-one; 8-Hydroxy-5-methyl-2H-chromen-2-one; 5-Methyl-8-oxo-2H-chromen-2-ol; Hymecromone Impurity (related compound)
EINECS	Contact for details

Quality Control

Our 5-Methyl-8-Hydroxycoumarin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	245 - 250 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.