Description

(21S)-17-Methoxy-21-Phenyl-1,21-Cycloaspidospermidine CAS NO 36528-88-8 is a complex, high-purity indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical advanced intermediate or reference standard for developing novel therapeutic agents, particularly in oncology and neurological research. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in cutting-edge medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel indole-based alkaloid derivatives with potential pharmacological activity.
• Medicinal Chemistry Research: Used as a reference compound or precursor in structure-activity relationship (SAR) studies for drug discovery programs.
• Process Development & Scale-Up: Serves as a critical material for optimizing synthetic routes and developing robust manufacturing processes for active pharmaceutical ingredients (APIs).
• Academic Research: Employed in university and institutional labs for studying complex alkaloid synthesis, natural product chemistry, and reaction mechanisms.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in analytical laboratories.
• Biochemical Tool Compound: Investigated for its biological activity and potential as a probe in cellular and biochemical assays.

Basic Information

Product Name	(21S)-17-Methoxy-21-Phenyl-1,21-Cycloaspidospermidine
CAS No.	36528-88-8
Molecular Formula	C28H32N2O
Molecular Weight	412.57 g/mol
Synonyms	17-Methoxy-21-phenyl-1,21-cycloaspidospermidine; (21S)-17-Methoxy-21-phenyl-1,21-cycloaspidospermidine; 1,21-Cycloaspidospermidine, 17-methoxy-21-phenyl-, (21S)-; Aspidospermidine derivative; Indole alkaloid intermediate; 36528-88-8; NSC 339539
EINECS	Contact for details

Quality Control

Our (21S)-17-Methoxy-21-Phenyl-1,21-Cycloaspidospermidine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support custom synthesis and purification to meet specific research-grade or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.