Description

D-1-(3,4,5-Trimethoxybenzyl)-6,7-Dihydroxy-1,2,3,4-Tetrahydroisoquinoline CAS NO 36478-07-6 is a chiral tetrahydroisoquinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of bioactive molecules. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the synthesis of complex drug candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of alkaloid-based drug candidates and central nervous system (CNS) active compounds.
• Research Chemical: Used in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new therapeutic agents.
• Chiral Building Block: Employed in asymmetric synthesis to construct complex molecules with defined stereochemistry for medicinal chemistry applications.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals, including dyes, ligands for catalysis, and advanced materials.
• Biochemical Research: Potential tool compound for investigating enzymatic pathways and receptor interactions due to its specific structural motifs.

Basic Information

Product Name	D-1-(3,4,5-Trimethoxybenzyl)-6,7-Dihydroxy-1,2,3,4-Tetrahydroisoquinoline
CAS No.	36478-07-6
Molecular Formula	C19H23NO5
Molecular Weight	345.39 g/mol
Synonyms	(R)-1-(3,4,5-Trimethoxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline; D-Tetrahydroisoquinoline derivative; (R)-6,7-Dihydroxy-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6,7-dihydroxy-1-[(3,4,5-trimethoxyphenyl)methyl]isoquinoline, (R)-; CAS 36478-07-6; (R)-TMBDHIQ; D-enantiomer of TMBDHIQ
EINECS	Contact for details

Quality Control

Our D-1-(3,4,5-Trimethoxybenzyl)-6,7-Dihydroxy-1,2,3,4-Tetrahydroisoquinoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric excess, meeting the stringent requirements for research and pharmaceutical applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.