Description

4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane is a versatile brominated acetal derivative, primarily valued as a key protected intermediate in organic synthesis. This compound is crucial for introducing functionalized alkyl chains while protecting aldehyde or ketone functionalities under a wide range of reaction conditions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for complex molecule assembly.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing bromomethyl functional groups in a protected form.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the dioxolane moiety offers stability during synthesis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers and resins with tailored properties.
• Material Science: Employed in surface modification and the creation of functional materials, including liquid crystals and organic electronic components.
• Organic Synthesis Reagent: A valuable reagent for nucleophilic substitution reactions (SN2), enabling the alkylation of various nucleophiles like amines, thiols, and stabilized carbanions.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex aroma chemicals and flavoring agents that require acetal-protected aldehydes.

Basic Information

Product Name	4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane
CAS No.	36236-76-7
Molecular Formula	C6H11BrO2
Molecular Weight	195.06 g/mol
Synonyms	2,2-Dimethyl-4-(bromomethyl)-1,3-dioxolane; 4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane; 1,3-Dioxolane, 4-(bromomethyl)-2,2-dimethyl-; Bromomethyl acetonide; (Bromomethyl)acetaldehyde dimethyl acetal (cyclic); 2-(Bromomethyl)-2-methyl-1,3-dioxolane; 4-Bromomethyl-2,2-dimethyl-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.460 - 1.470
Density (g/mL at 20°C)	1.40 - 1.50

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.