Description

1-(Chloromethyl)-3,4-Dihydroisoquinoline is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its reactive chloromethyl group fused to a dihydroisoquinoline scaffold, enabling its use as a key intermediate in the construction of complex nitrogen-containing molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and photoactive compounds.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	1-(Chloromethyl)-3,4-Dihydroisoquinoline
CAS No.	36177-79-4
Molecular Formula	C10H10ClN
Molecular Weight	179.65 g/mol
Synonyms	1-(Chloromethyl)-3,4-dihydroisoquinoline; 3,4-Dihydro-1-isoquinolinecarboxaldehyde, chloro-; 1-Chloromethyl-3,4-dihydroisoquinoline; 1-Chloromethyl-1,2,3,4-tetrahydroisoquinoline; Isoquinoline, 1-(chloromethyl)-3,4-dihydro-; 36177-79-4; NSC 163045
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-3,4-Dihydroisoquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.