Description

Borane, (1R,2S,4R)-Bicyclo[2.2.1]Hept-5-En-2-Yldichloro-, Rel- (9Ci) is a highly specialized chiral organoborane reagent, a key building block in asymmetric synthesis. Its value lies in its ability to introduce the norbornene framework with precise stereochemistry, enabling the creation of complex, enantiomerically pure molecules. This compound is essential for researchers and process chemists in the pharmaceutical and advanced materials sectors, particularly for developing novel active pharmaceutical ingredients (APIs) and chiral ligands.

Application

• Asymmetric Synthesis: A crucial chiral precursor for constructing enantiomerically enriched natural products and pharmaceutical intermediates.
• Pharmaceutical Research: Used in the development of novel APIs, especially those requiring the rigid, three-dimensional norbornene scaffold for biological activity.
• Catalyst and Ligand Development: Serves as a starting material for synthesizing sophisticated chiral ligands and organometallic catalysts.
• Advanced Material Science: Employed in the synthesis of specialty polymers and functional materials with specific stereochemical properties.
• Methodology Development: A valuable tool for academic and industrial research into new boron-mediated stereoselective transformations.
• Fine Chemical Production: Enables the commercial-scale manufacture of high-value, optically pure fine chemicals and agrochemicals.

Basic Information

Product Name	Borane, (1R,2S,4R)-Bicyclo[2.2.1]Hept-5-En-2-Yldichloro-, Rel- (9Ci)
CAS No.	36169-96-7
Molecular Formula	C7H9BCl2
Molecular Weight	174.86 g/mol
Synonyms	(1R,2S,4R)-5-Norbornene-2-dichloroborane; (1R,2S,4R)-2-(Dichloroboryl)bicyclo[2.2.1]hept-5-ene; rel-(1R,2S,4R)-Bicyclo[2.2.1]hept-5-ene-2-dichloroborane; (1R,2S,4R)-2-Dichloroboryl-5-norbornene; Chiral norbornenyl dichloroborane; Norborn-5-ene-2-dichloroborane, (1R,2S,4R)-rel-; Dichloro[(1R,2S,4R)-bicyclo[2.2.1]hept-5-en-2-yl]borane
EINECS	Contact for details

Quality Control

Every batch of our chiral organoborane reagents is produced and tested under strict quality management to ensure exceptional purity and stereochemical integrity, critical for sensitive asymmetric synthesis. We provide comprehensive Certificates of Analysis (COA) detailing chiral purity (enantiomeric excess), chemical purity, and identity confirmation via advanced analytical techniques. Our quality systems support development from research to commercial scale, with documentation tailored to meet GMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, containers must be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent decomposition. Isolate from incompatible materials such as strong oxidizers, acids, and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.