Description

3-Thiophenecarboxylic Acid, 5-Chloro-, Methyl Ester is a high-purity organic building block and key synthetic intermediate. This compound matters for its role in constructing complex heterocyclic molecules, particularly in advanced pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as the synthesis of active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those containing thiophene or chlorinated heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides.
• Material Science Research: Serves as a monomer or precursor for the development of conductive polymers, organic semiconductors, and specialty coatings.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions, such as Suzuki or Stille couplings, to create complex molecular architectures.
• Chemical Research & Development: A versatile reagent for academic and industrial labs exploring new synthetic methodologies and chemical entities.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands for metal-organic frameworks (MOFs) or transition metal catalysts.

Basic Information

Product Name	3-Thiophenecarboxylic Acid, 5-Chloro-, Methyl Ester
CAS No.	36157-43-4
Molecular Formula	C7H5ClO2S
Molecular Weight	188.63 g/mol
Synonyms	Methyl 5-chlorothiophene-3-carboxylate; 5-Chloro-3-thiophenecarboxylic acid methyl ester; 5-Chlorothiophene-3-carboxylic acid methyl ester; Methyl 5-chloro-3-thienoate; 3-Carbomethoxy-5-chlorothiophene; 5-Chloro-3-methoxycarbonylthiophene; 5-Chloro-3-thiophenecarboxylic Acid Methyl Ester; 5-Chloro-3-thienylcarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarboxylic Acid, 5-Chloro-, Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems support compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.