Description

5-Chlorothiophene-3-Carboxylic Acid is a versatile heterocyclic building block and key organic intermediate. This compound is valued for its reactive carboxylic acid and halogenated thiophene functionalities, enabling precise molecular construction. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Serves as a key building block for developing advanced pesticides, herbicides, and fungicides, leveraging the thiophene moiety for enhanced biological activity.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and other electronic materials where the thiophene core is essential for charge transport properties.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry and organic synthesis for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: The carboxylic acid group allows for derivatization into complex ligands used in coordination chemistry and catalytic processes.

Basic Information

Product Name	5-Chlorothiophene-3-Carboxylic Acid
CAS No.	36157-42-3
Molecular Formula	C5H3ClO2S
Molecular Weight	162.59 g/mol
Synonyms	3-Chloro-5-thiophenecarboxylic Acid; 5-Chloro-3-thiophenecarboxylic Acid; 5-Chlorothiophene-3-carboxylic acid; 3-Thiophenecarboxylic acid, 5-chloro-; 5-Chloro-3-thiophene carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Chlorothiophene-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.