Description

3-Bromo-4-Chlorothiophene is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in its dual reactive sites, which allow for selective functionalization and incorporation into complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the thiophene scaffold's bioactivity.
• Organic Electronic Materials: Serves as a monomer or building block for conjugated polymers and small molecules used in OLEDs (Organic Light-Emitting Diodes), organic photovoltaics, and semiconductor materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis, enabling novel synthetic transformations.
• Chemical Research & Development: A fundamental reagent for exploring new heterocyclic chemistry, cross-coupling reactions (e.g., Suzuki, Stille), and ring-forming methodologies.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized colorants and functional dyes with specific light-absorption properties.

Basic Information

Product Name	3-Bromo-4-Chlorothiophene
CAS No.	36155-88-1
Molecular Formula	C4H2BrClS
Molecular Weight	197.48 g/mol
Synonyms	4-Chloro-3-bromothiophene; 3-Bromo-4-chlorothiophene; Thiophene, 3-bromo-4-chloro-; 3-Bromo-4-chloro-thiophene; 4-Chloro-3-bromo-thiophene; 3-Br-4-Cl-thiophene
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chlorothiophene is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request and are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.