Description

3-Formyl-5-Methyl-2-Thiopheneboronic Acid is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. This compound matters because its unique structure, featuring both a formyl and a boronic acid group on a thiophene core, enables precise cross-coupling reactions and further functionalization. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and advanced functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in advanced herbicides, fungicides, and insecticides.
• Organic Electronic Materials: Serves as a building block for π-conjugated polymers and small molecules used in OLEDs, OFETs, and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of novel bidentate ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for studying biological pathways and protein interactions.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing thiophene and boronic acid functionalities into polymer backbones.

Basic Information

Product Name	3-Formyl-5-Methyl-2-Thiopheneboronic Acid
CAS No.	36155-76-7
Molecular Formula	C6H7BO3S
Molecular Weight	169.99 g/mol
Synonyms	(5-Methyl-3-formylthiophen-2-yl)boronic acid; 5-Methyl-3-formyl-2-thienylboronic acid; 2-Borono-5-methyl-3-thiophenecarboxaldehyde; 3-Formyl-5-methylthiophene-2-boronic acid; 5-Methyl-3-formylthiophene-2-boronic acid; 3-Formyl-5-methyl-2-thienylboronic acid; 2-Formyl-4-methyl-5-thienylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Formyl-5-Methyl-2-Thiopheneboronic Acid undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques, including HPLC, NMR, and IR spectroscopy, to verify identity, purity, and consistency across batches. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.