Description

1-(2-Methyl-3-Hydroxy-5-Hydroxymethyl-4-Pyridyl)-6,7-Dihydroxy-1,2-3,4-Tetrahydroisoquinoline is a complex heterocyclic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical intermediate or reference standard in the synthesis of bioactive compounds, particularly those targeting neurological and metabolic pathways. It is essential for research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of novel therapeutic agents and high-purity analytical standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially in central nervous system (CNS) and metabolic disorder research.
• Reference Standard: Used as a high-purity analytical standard in Quality Control (QC) and Quality Assurance (QA) laboratories for method development and validation.
• Biochemical Research: Employed in enzymatic studies and as a ligand or inhibitor in probing specific biological receptors and pathways.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex, functionalized tetrahydroisoquinoline and pyridine derivatives.
• Academic Research: Utilized in universities and R&D centers for studying structure-activity relationships (SAR) and novel organic reaction methodologies.

Basic Information

Product Name	1-(2-Methyl-3-Hydroxy-5-Hydroxymethyl-4-Pyridyl)-6,7-Dihydroxy-1,2-3,4-Tetrahydroisoquinoline
CAS No.	36120-58-8
Molecular Formula	C₁₇H₂₀N₂O₄
Molecular Weight	316.35 g/mol
Synonyms	6,7-Dihydroxy-1-(2-methyl-3-hydroxy-5-hydroxymethyl-4-pyridyl)-1,2,3,4-tetrahydroisoquinoline; 1-(2-Methyl-3,5-dihydroxy-4-pyridylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline; Tetrahydroisoquinoline pyridine derivative; THIQ-Pyridine derivative; CAS 36120-58-8
EINECS	Contact for details

Quality Control

Our 1-(2-Methyl-3-Hydroxy-5-Hydroxymethyl-4-Pyridyl)-6,7-Dihydroxy-1,2-3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep the container tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.