Description

4-Nitrobenzyl 2,3,4,6-Tetra-o-Acetyl-1-Thio-β-D-Galactopyranoside is a key thioglycoside building block extensively used in synthetic carbohydrate chemistry. This compound is crucial for the controlled synthesis of complex oligosaccharides and glycoconjugates, enabling the study of biological recognition processes. It is primarily utilized by research institutions and pharmaceutical companies engaged in glycoscience, glycobiology research, and the development of novel therapeutics and diagnostics.

Application

• Glycosylation Reagent: Acts as a versatile glycosyl donor in the stereoselective synthesis of β-linked galactosides and complex oligosaccharides.
• Glycoconjugate Synthesis: Used in the preparation of glycopeptides, glycolipids, and other biologically relevant glycoconjugates for structure-activity relationship studies.
• Enzyme Substrate/Inhibitor Development: Serves as a precursor or intermediate in the design and synthesis of substrates or inhibitors for glycosidases and glycosyltransferases.
• Chemical Biology Probes: Employed in the creation of activity-based probes and labeled sugars to study glycosylation pathways and carbohydrate-protein interactions in cells.
• Pharmaceutical Intermediate: A critical intermediate in the research and development stages of carbohydrate-based drugs, including antiviral and anticancer agents.
• Material Science: Potential use in the synthesis of functionalized polymers and surfaces with specific carbohydrate motifs for biosensing or biocompatibility applications.

Basic Information

Product Name	4-Nitrobenzyl 2,3,4,6-Tetra-o-Acetyl-1-Thio-β-D-Galactopyranoside
CAS No.	35785-42-3
Molecular Formula	C21H25NO11S
Molecular Weight	499.49 g/mol
Synonyms	1-Thio-β-D-galactopyranoside, 2,3,4,6-tetra-O-acetyl-, 4-nitrobenzyl ester; 4-Nitrobenzyl 1-Thio-β-D-galactopyranoside 2,3,4,6-Tetraacetate; p-Nitrobenzyl 2,3,4,6-Tetra-O-acetyl-1-thio-β-D-galactopyranoside; Galactose p-nitrobenzyl thio-glycoside tetraacetate; 1-S-(4-Nitrobenzyl) 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside; Thiogalactoside tetraacetate 4-nitrobenzyl ester
EINECS	Contact for details

Quality Control

Our 4-Nitrobenzyl 2,3,4,6-Tetra-o-Acetyl-1-Thio-β-D-Galactopyranoside is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is characterized by advanced analytical techniques including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled and stored under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.